Jonny Lee Miller
as Eli Stone
Natasha Henstridge
as Taylor Wethersby
Victor Garber
as Jordan Wethersby
Loretta Devine
as Patti Dellacoix
Sam Jaeger
as Matt Dowd
James Saito
as Dr. Frank Chen
Julie Gonzalo
as Maggie Dekker
Matt Letscher
as Dr. Nathan Stone
Jason George
as Keith Bennett
Laura Benanti
as Beth Keller